News
Berlin Cures advances fight against Long COVID on a pan-European level
14.12.2023 / Berlin Cures, a biotechnology company specialized in neutralizing functional autoantibodies (fAABs), is expanding its Phase II clinical trial into a pan-European, multi-center collaboration in the fight against Long COVID. A total of 12 sites in Germany, Austria, Switzerland, Finland and Spain are working to advance clinical research into this escalating global health problem. Additional trial sites in Switzerland, Spain and Germany are expected to soon follow. First results of the Phase II trial are expected in 2024. In the event of positive results, Berlin Cures is aiming for a larger Phase III study, which is a prerequisite for the approval of BC 007.
“We are delighted to have so many clinical institutions across Europe working with us towards transforming our platform technology into a therapeutic solution for millions of patients,” says Oliver von Stein, CEO of Berlin Cures. “As we intensify our efforts on a multinational scale, we’re aiming to provide a solution for Long COVID as well as to redefine the approach to multiple other fAAB-associated diseases such as heart failure or glaucoma. This pan-European collaboration symbolizes a united front against an urgent health crisis and underscores our dedication to innovation and impactful science.”
The expansion of the study to five countries across Europe marks an important step in the multinational approach of Berlin Cures’ Phase II trial BLOC. The study will provide meaningful and robust results on the efficacy and tolerability of the company’s lead drug candidate BC 007 in Long COVID patients.
As a platform technology, BC 007 has the potential to cure different autoimmune diseases by targeting fAABs as their root cause. The compound functions similarly to an antibody, binding and neutralizing harmful fAABs. In Long COVID, a considerable proportion of the diseases are due to the presence of fAABs. Berlin Cures aims to pioneer the development of a treatment based on BC 007 that addresses the core of fAAB-associated diseases, such as Long COVID, heart failure and glaucoma.
Overview of trial site locations:
Germany: 2x Berlin (recruiting), Cologne (recruiting), Münster (recruiting), Erlangen (active, starts recruiting soon)
Austria: 2x Vienna (recruiting)
Switzerland: Zurich (active, starts recruiting soon), Basel to follow soon
Spain: Valencia (recruiting), Pamplona (recruiting) Madrid (active, starts recruiting soon); Malaga and Seville to follow soon
Finland: Helsinki (active, starts recruiting soon)
All recruiting trial sites and participation criteria can be found on this page on clinicaltrials.gov.
Source: Berlin Cures
https://www.berlincures.com/en/news/advances-fight-against-long-covid-on-a-pan-european-level
